Y Combinator backed Play Health launches data-driven perimenopause platform
Combines at-home hormone testing, daily symptom and lifestyle tracking, and personalized insights.
Play Health, a Y Combinator–backed women’s health startup, has launched a new digital care platform designed to bring clarity and data-driven support to women experiencing perimenopause - one of the most misunderstood stages of life.
Perimenopause, the years leading up to menopause, affects all women but remains poorly understood and under-researched. Symptoms such as mood changes, disrupted sleep, and irregular cycles are common, yet many women struggle to access meaningful care or explanations.
Play Health aims to change that with a combination of at-home hormone testing, daily symptom and lifestyle tracking, and personalized insights that connect how women feel with what’s happening in their biology.
“There has been a gap in women’s midlife care, specifically perimenopause care, for far too long,” said Andrea Mazzocchi, PhD, Co-Founder and CEO of Play Health.
“We’ve built Play Health to change that. We’re connecting what’s biologically happening with how women feel every day. This helps women today and allows for the advancement of women’s health in the future.”
Building the dataset perimenopause has always needed
The platform allows users to log more than 40 symptoms, track cycles and lifestyle factors, and measure 12 key hormones and biomarkers via at-home tests. Over time, the app translates these data points into personalized insights and pattern recognition to help users understand what’s driving their symptoms.
“By pairing real-world symptom data with hormone trends over time, we’re not just helping women feel better today,” said Ian Miller, Co-Founder and CTO. “We’re laying the groundwork for tomorrow’s diagnostics, treatments, and standards of care.”
Unlike many consumer wellness apps, Play Health’s stated goal is to build the most comprehensive dataset on perimenopause to date - one that could inform future clinical research and more individualized care pathways.
From personal tracking to population-level insight
Traditional healthcare offers limited tools for perimenopause because providers rarely have access to longitudinal hormone data. Play Health’s founders - both serial entrepreneurs with experience in biotechnology and AI-driven health companies - believe this type of continuous data capture could help close that gap.
The company’s Founding Members program offers early access to pilot features, feedback circles, and exclusive pricing, signaling an emphasis on co-development with real users. Upcoming integrations with wearables such as Oura, Apple Health, Whoop, and Garmin will further expand data inputs.
Founded in 2025 and based in Boulder, Colorado, Play Health is part of a new wave of digital women’s health companies focusing on midlife care — an area historically underserved by both traditional medicine and healthtech investment.
While digital health tools for menopause have proliferated in recent years, few have attempted to quantify and connect biological and experiential data at this scale. The use of hormone assays alongside lifestyle tracking moves Play Health closer to a “digital biomarker” model - one that could ultimately inform clinical decision-making or guide new therapies.
Once fully up and running, Play Health’s approach could help women to make informed choices rather than simply manage symptoms.